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Scientific study reveals at what age a person is considered 'old'

Mar 17, 2024
3 min read

According to researchers, the aging process generally begins around the age of 34, reaching its peak after the age of 78. This conclusion was reached through the analysis of the varied levels of proteins found in the blood plasma of more than 4 thousand participants, whose ages ranged between 18 and 95 years.


373 proteins were identified whose changes are associated with the aging process - Photo Reproduction






A new scientific study is challenging long-held concepts about what it means to be "old." In Brazil, a person is classified as elderly at age 60, although there is a bill underway to increase this minimum age to 65. However, it is interesting to consider at what point in life the first signs of aging begin to appear in the body. According to studies carried out at Stanford University, on average, These signs begin to appear around age 34. The peak of old age, in turn, is generally reached after the age of 78.


The results, recently published in the scientific journal Nature Medicine, reveal surprising discoveries that could transform the way society views the aging process. In the article, researchers state that aging is a dominant risk factor for several chronic diseases that reduce life expectancy.


Deconstructing Social Stigmas


The concept of "old age" has historically been subjective and often associated with negative stereotypes such as physical frailty, cognitive decline and social isolation. However, This study challenges these preconceived notions by investigating age perception in a broad sample of the population. As the biological clock advances, several signs of aging become noticeable, such as facial wrinkles, gray hair, decreased hearing and vision, decreased agility and, occasionally, urinary incontinence.


However, experts argue that this process of external manifestation begins much earlier, occurring within the organism itself. The first changes begin around age 34 and continue until age 60., marking the phase known as adulthood. From 60 to 78 years old, the period of late maturity occurs. After the age of 78, old age finally arrives — the moment at which the person is considered "old".


Methodology and Sample


According to the researchers, determining the beginning of the aging process was not based on chronological age, that is, on counting the years lived. Instead, the analysis was conducted considering the varied levels of proteins present in blood plasma, excluding cells, from more than 4 thousand participants, whose ages ranged between 18 and 95 years. Also according to the study, as a person ages, the levels of 373 proteins decrease considerably in plasma until their production completely ceases. This is due to the deterioration of DNA repair capacity.


Tony Wyss-Coray, professor of neurology and study co-author, noted that the potential for measurements of certain blood proteins to provide insights into an individual's health has long been recognized. However, Historically, these measurements were conducted in isolation, without considering multiple proteins simultaneously. To establish a new perspective on aging, researchers carried out analyzes on 4,200 people of different age groups, evaluating the levels of 3,000 proteins.


Surprising Results


From this broad set of data, they identified 373 proteins whose changes are associated with the aging process. According to researcher Wyss-Coray, when substantial changes occur in the relative levels of proteins, this indicates a change in you too. Therefore, This approach offers a very reliable way of tracking the different stages of life of a person.


Based on these results and other investigations, Stanford scientists were able to create an artificial intelligence (AI) algorithm that can determine the biological age of each organ in an individual and predict the risk of failure of that organ. In the future, this technology could enable early interventions, preventing the development of diseases and, thus, increasing the quality of life for older people.


Social and Political Implications


These discoveries have profound implications for various aspects of society, from public policies related to health and well-being of the elderly to issues of age discrimination in the workplace and access to services. With a more accurate understanding of age perception, policymakers and healthcare professionals can tailor interventions and services to better meet people's needs as they age.


Paradigm change


This study challenges the traditional notion that old age begins at a specific, fixed age. Instead, it highlights the importance of considering each person's individuality and the factors that influence their aging experience. By recognizing this diversity, we can work toward a more inclusive and compassionate society where people of all ages are valued and respected for their unique contributions to the community.


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